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Detection
of neurodegeneration and amyloid plaques in the mouse brain of a model for
Alzeimer’s disease.
40 µm cryostat section was cut coronally through the dorsal
hippocampus of a transgenic mouse used as a model for studing Alzeimer’s
disease. The section was processed for detecting both neuronal damage and amyloid plaques with FD NeuroSilver™ Kit I.
Note silver-stained plaques in both the hippocampus and the cortex (click to
see enlarged photo). |
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High mignification of the hippocampal CA1 area as shown above. Note that in addition to silver-stained amyloid plaques, numerous degenerating fibers are also present in the corpus callosum (click to see enlarged photo). | ||